Research Article

Preparation and the Biopharmaceutical Evaluation for the Metered Dose Transdermal Spray of Dexketoprofen

Table 1

Composition of investigated formulation for excipients screening.

IngredientsF1F2F3F4F5F6F7F8F9F10

DE (%w/w)5555555555
PE (%v/v)555505
FFP (%w/w)5555000005
Absolute alcoholAdd to 10 mL

The FFPs used in F1 to F4 were Eudragit RL PO, Plasdone S-630, PVP K30, and Kollidone PF 12, respectively; the PEs used in F5 to F8 were AZO, IPM, LA and PG, respectively; F9 was used as the control group; F10 contained both PE and FFP.