Preparation and the Biopharmaceutical Evaluation for the Metered Dose Transdermal Spray of Dexketoprofen

Table 5

Gradient conditions for UPLC.

Inlet	Time (min)	Flow rate (mL/min)	A (%)^a	B (%)^b
1	Initial	0.3	60	40
2	0.5	0.3	40	60
3	2	0.3	5	95
4	3	0.3	5	95
5	3.2	0.3	60	40
6	4	0.3	60	40

a10 mM ammonium acetate buffer; ^bmethanol.