Research Article
Preparation and the Biopharmaceutical Evaluation for the Metered Dose Transdermal Spray of Dexketoprofen
Table 6
Solubility of DE in different solvents (
).
| | Solvents | Solubility (mg/mL) |
| | PBS (pH 6.5) | 33.73 ± 0.20 | | PBS (pH 7.0) | 63.26 ± 0.99 | | PBS (pH 7.4) | 78.89 ± 0.06 | | 20% PEG | 12.53 ± 3.33 | | 30% PEG | 28.76 ± 0.03 | | 40% PEG | 76.48 ± 0.13 | |
IPM
| 142.92 ± 5.51 | |
PG
| 252.61 ± 5.34 | |
AZO
| 22.37 ± 3.32 | |
LA
| 47.79 ± 5.61 |
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