Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases

Figure 6

Paclitaxel (PTX) staining in MDA-MB-231 lung metastasis. The H&E stain demonstrates human breast cancer MDA-MB-231 cells surrounding a blood vessel in the lung (a) and mononuclear cells adjacent to a blood vessel that are much smaller than breast cancer cells (b). The IHC stains demonstrate that the cytoplasm of rare scattered tumor cells is faintly stained brown by anti-rabbit IgG immunoglobulin, in contrast to the cells stained with anti-PTX antibody, which shows intense brown staining of the cytoplasm.

(a)

(b)