Research Article
Hydroxypropyl-β-cyclodextrin: A Novel Transungual Permeation Enhancer for Development of Topical Drug Delivery System for Onychomycosis
Table 2
Composition of nail lacquer drug delivery formulations of terbinafine hydrochloride for optimization of HP-
-CD concentration.
| Ingredient | Concentration (% w/v) | Formulation code | L6 | L7 | L8 | L9 | L10 |
| Terbinafine hydrochloride | 1 | 1 | 1 | 1 | 1 | Cellulose acetate | 2 | 2 | 2 | 2 | 2 | Triethyl citrate | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | Ethyl cellulose | 3 | 3 | 3 | 3 | 3 | Isopropyl alcohol | 30 | 30 | 30 | 30 | 30 | Acetone | 42.9 | 41.9 | 40.9 | 39.9 | 38.9 | Deionized water | 15 | 15 | 15 | 15 | 15 | HP--CD | 6 | 7 | 8 | 9 | 10 |
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