Research Article

High-Resolution Imaging of Polyethylene Glycol Coated Dendrimers via Combined Atomic Force and Scanning Tunneling Microscopy

Figure 4

High-resolution characterization of dendrimers with varying degrees of PEGylation. (a) A 60 × 60 nm2 STM topographic image of G4-PAMAM-NH2. (b) A 15 × 15 nm2 STM topographic image of G4-PAMAM-NH2 with three representative dendrimer contact areas highlighted in red. (c) 60 × 60 nm2 image of G4-PAMAM-50PEG1000. (d) 15 × 15 nm2 image of G4-PAMAM-50PEG1000 with two representative dendrimer/PEG contact areas highlighted in red. (e) 60 × 60 nm2 image of G4-PAMAM-6PEG1000. (f) 15 × 15 nm2 image of G4-PAMAM-6PEG1000 with two representative dendrimer/PEG contact areas highlighted in red. All images were acquired at 0.7–0.9 V and 20–30 pA.
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