Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate, Cetirizine Hydrochloride in Combined Pharmaceutical Dosage Form: A New Era in Novel Drug Delivery for Pediatrics and Geriatrics

Table 2

Formula for 1 tablet (200 mg) for the optimization of PVP K-30 or MCC with optimized concentration of SSG.

Serial number	Ingredients	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14
1	Salbutamol Sulphate	2	2	2	2	2	2	2	2	2	2	2	2	2	2
2	Cetirizine Hydrochloride	5	5	5	5	5	5	5	5	5	5	5	5	5	5
3	Sodium Starch Glycolate	8	8	8	8	8	8	8	8	8	8	8	8	8	8
4	Polyvinylpyrrolidone K-30	2	4	6	8	10	12	14	—	—	—	—	—	—	—
5	Microcrystalline Cellulose	—	—	—	—	—	—	—	2	4	6	8	10	12	14
6	Sodium Stearyl Fumarate	2	2	2	2	2	2	2	2	2	2	2	2	2	2
7	Talc	2	2	2	2	2	2	2	2	2	2	2	2	2	2
8	Sodium Saccharin	5	5	5	5	5	5	5	5	5	5	5	5	5	5
9	Mannitol	174	172	170	168	166	164	162	174	172	170	168	166	164	162