Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate, Cetirizine Hydrochloride in Combined Pharmaceutical Dosage Form: A New Era in Novel Drug Delivery for Pediatrics and Geriatrics

Table 5

Evaluation parameters for the optimization of Sodium Starch Glycolate.

Serial; number	Evaluation parameters	F1; (1%)	F2; (2%)	F3; (4%)	F4; (6%)	F5; (8%)	F6; (10%)
1	Weight variation (IP)	Passed	Passed	Passed	Passed	Passed	Passed
2	Friability (%)	0.8	0.8	0.1	0.3	0.1	0.1
3	Hardness (Kg/cm^2) ± S.D	2.2 ± 0.57	1.6 ± 0.28	1.5 ± 0.28	1.5 ± 0.32	2.0 ± 0.57	1.8 ± 0.28
4	Disintegration time (Sec) ± S.D	80 ± 2.34	59 ± 6.67	42 ± 3.56	49 ± 6.38	78 ± 7.39	95 ± 6.97

Average of three determinations.
Average of six determinations.