Solid Lipid Nanoparticles Improve the Diclofenac Availability in Vitreous after Intraocular Injection

Table 1

Mean size, polydispersity index (PDI), zeta potential, and encapsulation efficiency of solid lipid nanoparticles containing diclofenac after preparation and two-month storage at 2–8°C (mMean SD, ).

	After preparation	After one month	After two months
Mean size (nm)	172.7 6.3	216.4 10.2	269.5 2.8
PDI	0.254 0.001	0.184 0.044	0.150 0.083
Zeta potential (mV)	−0.9 2.0	−1.5 0.5	0.5 1.3
Encapsulation efficiency (%)	95.1 4.2	98.2 0.8	98.0 2.4