Poly(lactic-co-glycolic) Acid-Chitosan Dual Loaded Nanoparticles for Antiretroviral Nanoformulations

Figure 3

Size and PDI stability of NPs at different storage conditions; (a), (b), (c), and (f) were stable while (d) and (e) were unstable. Size is maintained after lyophilization (g and h). (a) PLGA-CS-NVP-LMV NPs stored at room temperature; (b) PLGA-CS-NVP NPs stored at room temperature; (c) PLGA-CS-LMV NPs lyophilized with 10% sucrose and stored at 4°C; (d) PLGA-CS-NVP-LMV NPs lyophilized without sucrose and stored at 4°C; (e) PLGA-CS-LMV NPs lyophilized without sucrose and stored at 4°C; (f) PLGA-CS-NVP NPs in 10% sucrose stored at −20°C; (g) PLGA-CS-NVP-LMV NPs lyophilized in 10% sucrose; (h) PLGA-CS-NVP NPs lyophilized in 10% sucrose.

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