Development of Oral Dissolvable Films of Diclofenac Sodium for Osteoarthritis Using Albizia and Khaya Gums as Hydrophilic Film Formers

Table 1

Composition of diclofenac sodium ODF formulations.

Code	Diclofenac sodium (g)	HPMC (g)	Albizia (g)	Khaya (g)	Gly (g)	Tw (g)	Fla (g)	Asp (g)	Tit (g)	CA (g)	Water (mL)
F1	4	3	—	—	5	1	5	1	1	1	100
F2	4	2	2	—	5	1	5	1	1	1	100
F3	4	2	—	5	5	1	5	1	1	1	100
F4	4	—	5	—	5	1	5	1	1	1	100
F5	4	—	2	5	5	1	5	1	1	1	100
F6	4	—		10	5	1	5	1	1	1	100
F7	4	1	2	5	5	1	5	1	1	1	100

Each 4 cm² film contains ~50 mg diclofenac sodium; Gly = glycerol; Tw = Tween 80; Fla = pineapple flavour; Asp = aspartame; Tit = titanium dioxide; and CA = citric acid.