Research Article
Development of Oral Dissolvable Films of Diclofenac Sodium for Osteoarthritis Using Albizia and Khaya Gums as Hydrophilic Film Formers
Table 2
Comparative physicochemical properties of purified
Albizia and
Khaya gums (mean ± SD,
).
| Parameter | Type of gum | Albizia | Khaya |
| Extraction yield (%) | 39.38 ± 2.35 | 67.50 ± 2.98 | Moisture content (%) | 12.42 ± 2.10 | 13.92 ± 1.51 | Insoluble matter (%) | 0.275 ± 0.041 | 0.282 ± 0.013 | pH (1% w/v @ 25°C) | 5.00 ± 0.12 | 3.84 ± 0.09 | Total ash (% w/w) | 7.853 ± 0.064 | 5.603 ± 0.023 | Water soluble ash (% w/w) | 1.303 ± 0.023 | 1.200 ± 0.017 | Acid insoluble ash (% w/w) | 0.600 ± 0.017 | 0.607 ± 0.012 | Solubility (%) | | | Cold water | 1.273 ± 0.064 | 0.380 ± 0.020 | Warm water | 1.747 ± 0.083 | 0.527 ± 0.064 | Acetone | 0.110 ± 0.044 | 0.127 ± 0.031 | Chloroform | 0.070 ± 0.062 | 0.020 ± 0.020 | Ethanol | 0.093 ± 0.023 | 0.087 ± 0.042 | Swelling index (%) | 611.29 ± 4.07 | 477.97 ± 8.67 | True density (g/mL) | 1.363 ± 0.012 | 1.412 ± 0.073 | Temperature of charring (°C) | 258.33 ± 2.89 | 242.67 ± 2.52 |
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