Research Article
Development of Oral Dissolvable Films of Diclofenac Sodium for Osteoarthritis Using Albizia and Khaya Gums as Hydrophilic Film Formers
Table 4
Physicochemical properties of diclofenac sodium ODF formulations.
| Code | Weight (g), | Thickness (mm), | pH, | Disintegration time (s), | Assay (%), |
| F1 | 0.186 ± 0.019 | 0.128 ± 0.013 | 4.66 ± 0.452 | 43.19 ± 0.077 | 98.74 ± 0.448 | F2 | 0.250 ± 0.016 | 0.128 ± 0.015 | 5.08 ± 0.181 | 37.16 ± 0.043 | 99.46 ± 0.337 | F3 | 0.194 ± 0.023 | 0.142 ± 0.008 | 4.82 ± 0.084 | 41.23 ± 0.070 | 99.94 ± 0.388 | F4 | 0.208 ± 0.019 | 0.138 ± 0.023 | 3.80 ± 0.035 | 40.32 ± 0.081 | 100.41 ± 0.212 | F5 | 0.254 ± 0.011 | 0.126 ± 0.013 | 3.09 ± 0.026 | 38.33 ± 0.053 | 99.68 ± 0.542 | F6 | 0.116 ± 0.011 | 0.108 ± 0.008 | 3.62 ± 0.060 | 43.13 ± 0.058 | 97.58 ± 0.231 | F7 | 0.298 ± 0.095 | 0.174 ± 0.011 | 5.23 ± 0.043 | 47.45 ± 0.050 | 98.82 ± 0.734 |
|
|
2 × 2 cm film.
|