Development of Oral Dissolvable Films of Diclofenac Sodium for Osteoarthritis Using Albizia and Khaya Gums as Hydrophilic Film Formers

Table 8

Drug release kinetic models of diclofenac sodium ODF formulations.

Code	Zero-order model		First-order model		Higuchi model		Hixson-Crowell model
	F1	32.54	0.8685	0.163	0.8580	34.46	0.9250	0.505	0.8615
F2	60.09	0.9834	0.979	0.9736	63.04	0.9989	0.865	0.9651
F3	87.18	0.9097	0.428	0.8860	85.29	0.9575	1.497	0.8942
F4	29.08	0.9793	0.146	0.9755	30.11	0.9938	0.976	0.9770
F5	57.79	0.9464	0.946	0.9400	58.80	0.9722	0.955	0.9601
F6	51.60	0.9144	0.266	0.9059	55.71	0.9554	0.893	0.9089
F7	92.40	0.9853	0.874	0.9704	96.24	0.9941	1.896	0.9753

, , , and are kinetic constants for zero-order, first-order, Higuchi, and Hixson-Crowell models, respectively; = correlation coefficient.