Formulation of Bilayer Benzydamine HCl Patch Targeted For Gingivitis

Table 2

Physical evaluation of double layer patches.

Batches	Appearance	Thickness; (mm)	Flatness; (%)	Surface pH	Moisture Loss; (%)	Moisture uptake (%)
						At 58% RH	At 79% RH
DL1	Thin, rigid, transparent		90.3	6-7	1.36	2.4	5.4
DL2	Thin, rigid, transparent		91.9	6-7	2.41	3.2	7.1
DL3	Thin, rigid, transparent		92.1	6-7	3.54	3.8	7.5
DL4	Thin, flexible, transparent		98.20	6-7	3.67	5.8	7.5
DL5	Thin, flexible, opaque		96.9	6-7	3.20	6.2	7.8
DL6	Thin, flexible, transparent		95	6-7	4.26	6.5	4.3
DL7	Thin, flexible, transparent		98.45	6-7	4.35	3.4	7.1
DL8	Thin, flexible, transparent		97.94	6-7	3.98	4.6	5.1
DL9	Thin, flexible, transparent		98.93	6-7	3.55	5.4	6.4