PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery

Table 1

Charge-based protein interaction.

Role	Protein	pI	Medium condition
			pH 7.4		pH 4
			Net charge	KTN interaction	Net charge	KTN interaction
Scaffold	Keratin (KTN)	5.3	−	Repulsion	+	Repulsion
Drug load	Albumin	~5	−	Repulsion	+	Repulsion
Drug load	Hemoglobin	~7	0	None	+	Repulsion
Drug load	Lysozyme	~11	+	Attraction	+	Repulsion