Investigation of Diffusion Characteristics through Microfluidic Channels for Passive Drug Delivery Applications

Table 5

Fraction of estimated delivered drug to required dosing rate for each design for commonly used drugs. Ratio is given by delivery drug/recommended dose.

Device	Design	Macugen	Lucentis	Intravitreal Avastin	Fluocinolone acetonide
TB	Straight	0.108	1.292	0.964	0.002
	Leaf	0.096	1.146	0.855	0.002
	Snake	0.046	0.551	0.411	0.001
TB-PEG	Straight	0.098	1.168	0.872	0.002
	Leaf	0.107	1.277	0.953	0.002
	Snake	0.047	0.566	0.422	0.001
RB	Straight	23.81	285.00	212.00	0.462
	Leaf	23.81	285.26	212.86	0.462
	Snake	23.81	285.26	212.86	0.462
RB-PEG	Straight	23.81	285.26	212.86	0.462
	Leaf	23.81	285.26	212.86	0.462
	Snake	23.81	285.26	212.86	0.462