Design, Characterization, and Optimization of Controlled Drug Delivery System Containing Antibiotic Drug/s

Table 7

Physiochemical parameters of factorial batches.

Batch code	Diameter (mm)	Thickness (mm)	Hardness (kg/cm^2)	% friability	Uniformity of weight (mg)	% drug content (% w/w)
F1	10.0 ± 0.05	5.2 ± 0.5	6.3 ± 0.2	0.54	540 ± 2.7	103.2 ± 2.1
F2	10.1 ± 0.05	4.9 ± 0.5	6.8 ± 0.4	0.39	470 ± 4.8	99.3 ± 3.6
F3	10.1 ± 0.05	5.1 ± 0.2	6.5 ± 0.5	0.72	530 ± 2.9	98.2 ± 4.3
F4	10.1 ± 0.05	5.2 ± 0.5	6.3 ± 0.7	0.43	540 ± 3.1	97.3 ± 4.7
F5	10.0 ± 0.05	4.6 ± 0.4	6.8 ± 0.3	0.11	385 ± 3.4	100.3 ± 2.2
F6	10.0 ± 0.05	5.4 ± 0.3	6.9 ± 0.2	0.47	590 ± 1.8	99.5 ± 1.4
F7	10.1 ± 0.05	4.7 ± 0.5	6.8 ± 0.2	0.52	380 ± 4.4	101.4 ± 1.2
F8	10.0 ± 0.05	4.9 ± 0.5	6.8 ± 0.5	0.65	500 ± 2.5	96.3 ± 3.3
F9	10.0 ± 0.05	4.8 ± 0.4	6.5 ± 0.2	0.83	430 ± 3.7	98.4 ± 1.4
F10	10.0 ± 0.05	5.2 ± 0.2	6.8 ± 0.4	0.49	540 ± 1.2	99.2 ± 3.8
F11	10.1 ± 0.05	4.8 ± 0.5	6.8 ± 0.5	0.57	430 ± 5.1	97.7 ± 2.6
F12	10.0 ± 0.05	4.8 ± 0.5	6.5 ± 0.3	0.34	440 ± 2.9	97.2 ± 1.3

All values are mean of three readings.