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Journal of Drug Delivery
Volume 2017 (2017), Article ID 7275985, 9 pages
https://doi.org/10.1155/2017/7275985
Review Article

Recent Advances in Hydrogel-Based Drug Delivery for Melanoma Cancer Therapy: A Mini Review

1St. Peters Institute of Pharmaceutical Sciences, Kakatiya University, Warangal, Telangana, India
2Department of Chemistry, Tulane University, New Orleans, LA, USA
3Laboratory of Nanobiomaterials, Institute of Chemistry and Natural Resources and Núcleo Científico Multidisciplinario, Universidad de Talca, Talca, Maule, Chile

Correspondence should be addressed to Esteban F. DurĂ¡n-Lara; lc.aclatu@narude

Received 10 March 2017; Revised 6 June 2017; Accepted 20 June 2017; Published 9 August 2017

Academic Editor: A. Fadda

Copyright © 2017 Sowmya Vishnubhakthula et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The purpose of this study is to describe some of the latest advances in using hydrogels for cancer melanoma therapy. Hydrogel formulations of polymeric material from natural or synthetic sources combined with therapeutic agents have gained great attention in the recent years for treating various maladies. These formulations can be categorized according to the strategies that induce cancer cell death in melanoma. First of all, we should note that these formulations can only play a supporting role that releases bioactive agents against cancer cells rather than the main role. This strategy involves delivering the drug via transdermal pathways, resulting in the death of cancerous cells. Another strategy utilizes magnetic gel composites to combat melanoma via hyperthermia therapy. This review discusses both transdermal and hyperthermia therapies and the recent advances that have occurred in the field.