In Vitro Evaluation of Cocoa Pod Husk Pectin as a Carrier for Chronodelivery of Hydrocortisone Intended for Adrenal Insufficiency

Table 3

Kinetic parameters of CPH pectin-based hydrocortisone matrix tablets.

Code	Zero order		First order		Higuchi model		Hixson-Crowell		Korsmeyer-Peppas
	F2
F3
F4
F5
F6
F7

(a) Film-coated HWSP-based hydrocortisone matrix tablets prepared by wet granulation (25% w/w weight gain); (b) film-coated CASP-based hydrocortisone matrix tablets prepared by wet granulation (25% w/w weight gain); (c) , , , are kinetic constants for zero order, first order, Hixson-Crowell, and Higuchi models, respectively; is the correlation coefficient; is the release exponent.