Research Article
Evaluation of Chitosan-Microcrystalline Cellulose Blends as Direct Compression Excipients
Table 3
Physical and mechanical properties of tablets.
| Batches | Compact density (g/cm3) | Tensile strength (kg/cm2) | Tablet porosity | Disintegration time (min) |
| F1 | 1.18 ± 0.01 | 8.65 ± 0.71 | 0.45 ± 0.02 | 2.43 ± 0.07 | F2 | 1.01 ± 0.02 | 4.33 ± 0.41 | 0.49 ± 0.01 | 0.38 ± 0.05 | F3 | 1.04 ± 0.02 | 4.33 ± 0.41 | 0.48 ± 0.01 | 1.08 ± 0.23 | F4 | 1.20 ± 0.02 | 4.15 ± 0.52 | 0.45 ± 0.01 | 2.12 ± 0.48 | F5 | 1.23 ± 0.02 | 3.49 ± 0.26 | 0.40 ± 0.01 | >60 | F6 | 1.16 ± 0.03 | 7.54 ± 0.77 | 0.43 ± 0.01 | 2.38 ± 0.04 | F7 | 1.15 ± 0.01 | 6.93 ± 0.75 | 0.41 ± 0.02 | 2.09 ± 0.30 | F8 | 1.12 ± 0.03 | 6.64 ± 0.95 | 0.41 ± 0.02 | 1.18 ± 0.30 | F9 | 1.09 ± 0.03 | 6.10 ± 0.32 | 0.40 ± 0.00 | 0.42 ± 0.04 |
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