Epidermal Growth Factor Receptor Protein: A Biological Marker for Oral Precancer and Cancer

Table 4

(a) Quantitative assessment of EGFR in histological types of oral leukoplakia. (b) Multiple comparisons between the three histological grades of dysplasia.

(a)

Serial number	Extent of EGFR expression	Moderate (𝑛=5)		Severe (𝑛=5)		Mild (𝑛=5)
		Number	%	Number	%	Number	%
1	0–25%	3	60	0	0	5	100
2	26–50%	1	20	5	100	0	0
3	51–75%	1	20	0	0	0	0
4	>75%	0	0	0	0	0	0
Mean ± SD		27.6±20.9		32.0±4.5		14.2±3.9
Range		10–58		30–40		10–18

𝜒²=13.750; 𝑃=0.008.

(b)

Serial number	Comparison	𝑍	𝑃
1	Moderate dysplasia versus severe dysplasia	0.651	0.548
2	Moderate dysplasia versus mild dysplasia	0.970	0.332
3	Severe dysplasia versus mild dysplasia	2.703	0.008

Mann-Whitney 𝑈 test used.