Topological Indices of Novel Drugs Used in Diabetes Treatment and Their QSPR Modeling

Table 17

Comparison of actual and computed values for refractive index from regression models.

Name of drug	Refractivity of drug	Refractivity computed from regression model for ABC(G) index	Refractivity computed from regression model for R(G) index	Refractivity computed from regression model for S(G) index	Refractivity computed from regression model for GA(G) index	Refractivity computed from regression model for M1(G) index	Refractivity computed from regression model for M2(G) index	Refractivity computed from regression model for F(G) index	Refractivity computed from regression model for H(G) index	Refractivity computed from regression model for HM(G) index
Acarbose	139.02	155.534	160.469	159.089	158.081	156.566	158.069	157.417	156.732	161.762
Tolazamide	81.34	87.0728	86.0361	85.8203	86.0013	87.662	88.505	89.041	88.344	85.2994
Miglitol	48.16	66.8545	69.0227	68.0669	68.0110	69.914	73.545	73.501	73.174	69.3471
Prandin	131.83	130.774	130.808	130.167	129.418	127.856	125.718	125.597	124.916	130.191
Metformin	56.64	49.4407	50.6662	49.9496	49.394	49.556	49.983	50.857	50.296	50.8057
Glimepiride	129.8	130.063	127.935	127.402	126.928	128.378	126.84	128.705	127.048	126.099
Linagliptin	133.43	123.700	122.189	123.582	123.794	121.592	118.799	117.901	117.618	122.925
Pioglitazone	97.39	92.2844	92.7146	93.4237	93.4718	91.316	90.749	89.189	89.41	93.5679
Bromocriptine	165.51	157.9	153.567	155.451	157.267	159.698	161.248	159.785	159.438	152.700
Alogliptin	104.26	93.6658	94.0577	94.3332	94.8948	93.926	94.863	92.889	93.264	94.6119