Table of Contents
Journal of Medical Engineering
Volume 2015, Article ID 636075, 5 pages
http://dx.doi.org/10.1155/2015/636075
Research Article

Electrical Bioimpedance Analysis: A New Method in Cervical Cancer Screening

1School of Medical Science & Technology, Indian Institute of Technology, Kharagpur 721302, India
2Department of Material Engineering, Indian Institute of Science, Bangalore 560012, India

Received 16 September 2014; Revised 17 December 2014; Accepted 19 January 2015

Academic Editor: Nicusor Iftimia

Copyright © 2015 Lopamudra Das et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cervical cancer is the second most common female cancer worldwide and a disease of concern due to its high rate of incidence of about 500,000 women annually and is responsible for about 280,000 deaths in a year. The mortality and morbidity of cervical cancer are reduced through mass screening via Pap smear, but this technique suffers from very high false negativity of around 30% to 40% and hence the sensitivity of this technique is not more than 60%. Electrical bioimpedance study employing cytosensors over a frequency range offers instantaneous and quantitative means to monitor cellular events and is an upcoming technique in real time to classify cells as normal and abnormal ones. This technology is exploited for label-free detection of diseases by identifying and measuring nonbiological parameters of the cell which may carry the disease signature.