Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research

Figure 9

Effect of ethanol on mouse fetal brain development at GD14.5. Left panel represents OCT images (a) and (b) in horizontal section, middle panel shows US images (c) and (d) in the coronal plane, and right panel illustrates H&E images (e) and (f) in sagittal section of fetal brains from both control and ethanol treated pregnant dams. Ethanol induced increase in ventricular dilation can be observed with all the imaging techniques used in the study and in all three planes of orientation. LV, lateral ventricles; US, ultrasound; OCT, optical coherence tomography; H&E, hematoxylin-eosin staining. Scale bar, 500 μm (reprinted with permission from [94]).