Optimizing Containment and Control of Candida parapsilosis Fungemia among Neonates in the Outbreak Setting Using a Mathematical Modeling Approach
Compartmental model for Candida blood stream infections. Proportion of neonates () in the NICU by compartment (“” = susceptibles; “” = colonized but not infected; “” = infected with disease). “” = reservoir fomite—a colonizing pressure function and not a true state variable. The parameters are: a = admission rate, m = nondisease causing mortality rate, μ = disease causing mortality rate, = exogenous transmission rate, = endogenous transmission rate, = colonization rate, = recovery rate, r = readmission rate, d = discharge rate, = fomite generation rate, and = fomite decay rate. Dashed lines represent contributions to the generation of the colonizing pressure, “,” and not transition through it.