Optimizing Containment and Control of Candida parapsilosis Fungemia among Neonates in the Outbreak Setting Using a Mathematical Modeling Approach
The critical proportion () requiring systemic fluconazole or selective digestive decontamination (SDD) with nystatin prophylaxis in order to stop an outbreak of C. parapsilosis fungemia in a neonatal intensive care unit (NICU) as a function of the basic reproductive number (). The to receive either prophylaxis was approximately the same unless increased greatly (as one begins to see with the exogenous (e.g., Huang et al. ) compared with endogenous outbreaks (e.g., Saxen et al. ) of candidemia examples) and the limit of approached zero (where is the efficacy in reducing colonization and is the efficacy in reducing infection).