Table of Contents
Journal of Mycology
Volume 2013, Article ID 832521, 11 pages
Review Article

Functions, Cooperation, and Interplays of the Vegetative Growth Signaling Pathway in the Aspergilli

Department of Microbial Biotechnology and Cell Biology, Faculty of Science and Technology, University of Debrecen, Debrecen 4032, Hungary

Received 28 April 2013; Revised 31 July 2013; Accepted 18 August 2013

Academic Editor: Thierry Jouault

Copyright © 2013 Tünde Pusztahelyi and István Pócsi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Knowledge on the functions, cooperation, and interplays of the signaling and regulatory pathways of filamentous fungi is crucial when their industrial performance is improved or when new-type antifungals are developed. Many research groups aim at a deeper understanding of vegetative growth signaling because this cascade also influences other important physiological processes including asexual and sexual developments, autolysis and apoptotic cell death as well as the production of a wide array of important secondary metabolites. This review also focuses on how this signaling pathway is interconnected with other signaling cascades setting up a robust but delicately regulated signaling network in the Aspergilli.