Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes
Figure 2
(a) CD spectra for the 27Bcl2 mid promoter sequence, wavelength in nm is plotted on -axis, and Ellipticity, , is plotted on the -axis in mdeg. The M quadruplex DNA is considered for each CD experiment. CD spectra are recorded at and quadruplex DNA: TMPyP4 stoichiometry. Each spectrum is recorded thrice, and the average of the three runs is considered. (b) CD spectra for the C-myc sequence, wavelength in nm is plotted on -axis and Ellipticity, , is plotted on the -axis in mdeg. The M quadruplex DNA is considered for each CD experiment. CD spectra are recorded at and quadruplex DNA: TMPyP4 stoichiometry. Each spectrum is recorded thrice, and the average of the three runs is considered.
