Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes

Table 2

Data obtained from Job plot of Bcl2 and C-myc G-quadruplex DNA with TMPyP4, TMPyP3, and TMPyP2 porphyrin drugs.

S. No.	Name of gquadrupelx DNA and porphyrin	Value of mole fraction of porphyrin matching with point of intersection	Stoichiometry between gquadruplex DNA porphyrin
1.	27Bcl2-TMPyP4	0.78	1∶3.54
2.	27Bcl2-TMPyP3	0.70	1∶2.33
3.	27Bcl2-TMPyP2	0.58	1∶1.38
4.	C-myc-TMPyP4	0.76	1∶3.17
5.	C-myc-TMPyP3	0.70	1∶2.33
6.	C-myc-TMPyP2	0.58	1∶1.38