Research Article

Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response

Figure 3

Structures of reserpine (a) and rescinnamine (b) analyzed by computational modeling depicting favorable (red) and unfavorable (blue) interactions with amino acids within MutS-binding pocket. Green indicates interactions of intermediate binding relevance.
162018.fig.003a
(a)
162018.fig.003b
(b)