Base Sequence Context Effects on Nucleotide Excision Repair
Figure 2
Effects of nearby guanine amino groups on the positioning of the 10S ()-trans-anti-B[a]P--dG adduct in the minor groove of the lesion-containing duplexes. The presence or absence and exact location of the guanine amino groups is governed by the base sequence contexts and determines the structural distortion/destabilization of the damaged duplexes. The damaged strand is light grey, and the partner is dark grey.
