Research Article
Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)]4
Table 1
Thermodynamic parameters for the interaction of compound 1 and netropsin with [d(TGGGGT)]4 determined by ITC at and pH 7.0.
| Ligand | | ( 106 M-1) | (kJ mol-1) | (kJ mol-1) | (kJ mol-1) |
| Compound 1 | 2.0 0.1 | 1.9 0.2 | −11.0 2.0 | 25 2 | −36 2 | Netropsin | 2.0 0.1 | 1.2 0.1 | −10.6 1.0 | 23 2 | −34 2 |
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