DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences
Other DNA alkylating agents inducing local destabilization of the DNA helix. (a) Structures of some DNA alkylating molecules that destabilize the DNA helix. (b) Three-dimensional organization of the psoralen derivative HMT (a) and -anti-BPDE (b) bound to DNA (crystallographic data [mmdbId:52343  and [mmdbId:52106, respectively, ).
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