Research Article

Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion

Figure 2

Frequency of HR in mouse RPE. (a) Population distribution of eye spots per RPE in wild-type (open boxes) and W r n Δ h e l / Δ h e l (grey boxes). (b) Overall frequency of eye spots per RPE shown as a box and whisker plot. No statistical difference in HR was detected between wild-type and W r n Δ h e l / Δ h e l groups ( 𝑃 = . 3 5 ).
356917.fig.002a
(a)
356917.fig.002b
(b)