Research Article

Aflatoxin B1-Associated DNA Adducts Stall S Phase and Stimulate Rad51 foci in Saccharomyces cerevisiae

Table 2

AFB1-N7 Guanine adducts in wild type and the rad4 mutant.

Genotype (Strain) aTotal AFB1-N7 Guanine adducts/mg DNAbRatioc

RAD4 (YB163) 7 . 2 × 1 0 3  nmol1
rad4::KanMX (YB225) 2 1 . 7 × 1 0 3  nmol3
Rad51-YFP (LSY1957) 4 . 6 × 1 0 3  nmol0.7

a Relevant genotype, see Table 1 for complete genotype,
b 𝑛 = 2 ,
c Ratio: AFB1 adduct in strain or rad mutant/AFB1 adduct in wild type (YB163).