“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles

Figure 7

Stabilisation of F21T oligonucleotide (Δ𝑇_1/2, ^∘C) induced by CBI and CTI macrocycles (1𝜇M) in (a) Na⁺- and (b) K⁺-rich conditions, for experiments carried out in the absence (black bars) or in the presence of 3 (dark green bars) or 10𝜇M (light green bars) of the duplex competitor (ds26).

(a)

(b)