Structure and Stability of a Dimeric G-Quadruplex Formed by Cyclic Oligonucleotides

<table>Schematic model of the dimeric structure of d<svg height="8.8500004" id="M24" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 10.825 8.8500004" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,8.85)">
<g transform="translate(72,-64.92)">
<text transform="matrix(1,0,0,-1,-71.95,65.27)">
<tspan style="font-size: 12.50px; " x="0" y="0">&lt;</tspan>
</text>
</g>
</g>
</svg>pGGGTTAGGGTTA<svg height="8.8500004" id="M25" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 10.825 8.8500004" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,8.85)">
<g transform="translate(72,-64.92)">
<text transform="matrix(1,0,0,-1,-71.95,65.27)">
<tspan style="font-size: 12.50px; " x="0" y="0">&gt;</tspan>
</text>
</g>
</g>
</svg>, consistent with the experimental data in Na<sup>+</sup> buffer. Guanines <i>syn</i> and <i>anti</i> are indicated with open and solid rectangles, respectively.</table>

Journal of Nucleic Acids

fig4

Figure 4

Figure 4: Structure and Stability of a Dimeric G-Quadruplex Formed by Cyclic Oligonucleotides 