Journal of Nucleic Acids / 2010 / Article / Tab 2

Research Article

Synthesis and G-Quadruplex-Binding Properties of Defined Acridine Oligomers

Table 2

Logarithm of the binding constants (log 𝐾 ) calculated from data recorded throughout fluorescence titrations using Equispec program assuming a 1 : 1 stoichiometry DNA : ligand for the interaction complex (details in materials and methods). Compounds 1–4 correspond to the acridine dimers and trimers prepared in this study. HT24, 24bcl, cmyc, and Dickerson correspond to oligonucleotide sequences shown in Table 1.

1234

HT244.9 ± 0.44.6 ± 0.55.3 ± 0.3n.d.
24bcl6.8 ± 0.55.1 ± 0.15.3 ± 0.2n.d.
cmyc5.5 ± 0.34.9 ± 0.24.8 ± 0.55.3 ± 0.2
Dickersonn.d.n.d.n.d.n.d.

n.d. not determined.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.