Review Article

One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition

Figure 1

Schematic representation of the folding of an oligonucleotide that mimics the human telomeric sequence (d[ A G 3 ( T 2 A G 3 ) 3 ]). The polymorphism of the quadruplex is represented through the various possible structures, namely, the hybrid (left), antiparallel (centre), and parallel (right) forms; these structures differ by strand orientation (grey dashed arrows) and loop arrangement (represented in orange, yellow, and red).
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