Is the Comet Assay a Sensitive Procedure for Detecting Genotoxicity?

Table 1

LGDs for Comet assay, Comet assay/araC, acellular assay, and MN test using TK6 cells.

Mutagen	LGD (𝜇g/mL or J/m^2)				Ratio of LGD
	Comet assay	Comet assay/araC	acellular assay	MN test	(Comet assay: MN test)
UVC	20	2.5	—	15	1.3
MNU	25	3.125	6.25	12.5	2
ENU	250	62.5	31.3	125	2
MMS	40	20	10	20	2
EMS	125	62.5	62.5	125	1
BLM	12.5	6.25	0.0625	5	2.5