Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining

<table>Crystal structures of LigIV/XRCC4 and Lif1p-Lig4p. Conserved XRCC4 or Lif1 interaction region of LigIV (XIR) or Lig4p (LIR) are indicated with blue arrows. (a) XRCC4(residues 1–213)(blue) and XIR (violet) (PDB code: 1IK9). (b) XRCC(residues 1–203)(blue) and BRCT domains of LigIV(residues 654–911)(violet) (PDB code: 3II6) (c) Lif1p(residues 1–246)(blue) and BRCT domains of Lig4p(residues 680–944)(violet).</table>

Journal of Nucleic Acids

fig12

Figure 12

Figure 12: Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining 