Research Article

Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana

Table 1

Comparison of nucleotide incorporation into lesion-containing template-primers between HsPol 𝜂 and ApPol 𝜂 .

DNA lesionHsPol 𝜂 ApPol 𝜂

CPDAA [710]AA
6−4 pp - - - a [9, 10] - - - a
Dewar - - - a , b - - - a
5R-TgA [15]A
5S-TgA [15]A
8-oxoGC/A [16, 17]C/A
AP site analog - - - a [10, 17] - - - a

a n o incorporation; b u npublished result.