| | Author, published year (reference no.) | Ethnicity | No. of Cases/controls | Source of controls | OR (95% CI) |
Quality control of genotyping | | Asp/Asn | Asn/Asn | |
| | Butkiewicz et al., 2001 [54] | Caucasian | | Population | 0.49
(0.24–0.98) | 0.71
(0.29–1.74) |
Sequencing | | Spitz et al., 2001 [55] | Admixed population | | Population | 0.92
(0.62–1.36) | 1.54
(0.78–3.05) |
None | | Hou et al., 2002 [56] | Caucasian | | Population | 1.27
(0.78–2.05) | 0.88
(0.43–1.84) |
Replication (random samples) | | Zhou et al., 2002 [57] | Caucasian | 1,092/1,240 | Population | 0.98
(0.82–1.17) | 1.41
(1.06–1.86) |
Replication (random samples) | | Liang et al., 2003 [58] | Asian | 1,006/1,020 | Population | 0.98
(0.76–1.28) | 11.2
(1.45–87.2) |
Replication (random samples) | | Misra et al., 2003 [39] | Caucasian | | Population | 0.76
(0.53–1.07) | 0.94
(0.56–1.59) |
Replication (random samples) | | Popanda et al., 2004 [42] | Caucasian | | Hospital | 1.14
(0.77–1.68) | 1.03
(0.70–1.51) |
Replication (random samples) | | Vogel et al., 2004 [59] | Caucasian | | Population | 1.27
(0.86–1.89) | 1.09
(0.63–1.86) |
None | | Shen et al., 2005 [60] | Asian | | Population | 0.58
(0.21–1.52) | |
Replication (random samples) | | Zienolddiny et al., 2006 [26] | Caucasian | | Population | 0.85
(0.58–1.25) | 1.11
(0.68–1.81) |
Replication (all samples) | | Matullo et al., 2006 [27] | Caucasian | | Population | 0.81
(0.52– 1.26) | 0.95
(0.51–1.71) |
Replication (random samples) | | Hu et al., 2006 [61] | Asian | | Hospital | 1.07
(0.81–1.43) | 4.11
(0.41–202.7) |
None | | López-Cima et al., 2007 [48] | Caucasian | | Hospital | 1.04
(0.80–1.35) | 1.39
(0.88–2.20) |
Sequencing | | De Ruyck et al., 2007 [30] | Caucasian | | Hospital | 1.28
(0.70–2.35) | 1.03
(0.40–2.66) |
None | | Chang et al.,2008 [62] | Latino | | Population | 1.37
(0.83–2.26) | 2.13
(0.72–5.96) |
Replication (random samples) | | Chang et al.,2008 [62] | African-American | | Population | 1.10
(0.71–1.70) | 0.68
(0.10–3.57) |
Replication (random samples) | | Yin et al., 2009 [63] | Asian | | Hospital | 1.31
(0.77–2.77) | |
Replication (random samples) |
| | Summary | No. of populations | | | | |
Cochran test for heterogeneity | | | | | | | Asp/Asn | Asn/Asn |
| | All | 17 (15) | 6,346/7,792 | | 1.00
(0.92–1.10) | 1.19
(1.03–1.38) | 0.510 | 0.510 | | Caucasian | 10 | 3,417/4,557 | | 0.98
(0.86–1.11) | 1.15
(0.98–1.34) | 0.257 | 0.770 | | Asian | 4 (2) | 2,379/2,404 | | 1.02
(0.85–1.22) | 8.26
(1.50–45.6) | 0.565 | 0.597 |
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