Journal of Nucleic Acids / 2010 / Article / Tab 1 / Research Article
Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation siRNA Sense strand
(
a
)
,
(
b
)
Antisense strand
(
a
)
,
(
b
)
Prevention of UV-TLS (result) siRev3-A gcuuuacaugagauacaaaTT uuuguaucucauguaaagcTT significant siRev3-B gacaguuuucagucaagauTT aucuugacugaaaacugucTT significant siRev3-C gagguaugauccugauauuTT aauaucaggaucauaccucTT significant siRev3-D guauugacuuaugucggauTT auccgacauaagucaauacTT significant siRev3cont-A ggu g a ac aucgu u c ac no effect siRev3cont-B gg g ac aucgu c c no effect siRev3cont-C guauugag c gauTT aucg c no effect siRev7-A gauccaggucaucaaggauTT auccuugaugaccuggaucTT partial siRev7-B gaugcagcuuuacguggaaTT uuccacguaaagcugcaucTT significant siRev7-C cacugucugucucaaauacTT guauuugagacagacagugTT significant siRev7cont-A gaugcagg c gaaTT uucg c cugcaucTT no effect siRev1-A cacauauuauugccacaaaTT c c cg uuuguggcaauaauaugugTTcg g g significant siPol
𝜂
-4
𝜂
-A
𝜂
-B
𝜂
cont-A uaaaccuugugcaguuguaTT g c uacaacugcacaagguuuaTTg c partial siPol
𝜄
-A
𝜄
-5 gccucauacagugagauuaTT uaaucucacuguaugaggcTT no effect siPol
𝜅
-A
𝜅
-B
𝜅
-C
𝜅
cont-B gagaaaauuaacaaaauuaTT g gc uaauuuuguuaauuuucucTTgc c partial
(
a
)
Small letters mean ribonucleotides, and large letters mean deoxyribonucleotides.
(
b
)
Mismatched bases are illustrated in bold and italic letters.
