Influence of <i>XRCC1</i> Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair

<table>Human XRCC1 protein and gene structure. (a) The diagram shows XRCC1 domains and the regions of interaction with other components of BER. (b) The diagram shows the structure of the gene with  the most common and studied single nucleotide polymorphisms (SNPs): −77 <svg height="10.9125" id="M2" style="vertical-align:-0.17554pt" version="1.1" viewbox="0 0 48.462502 10.9125" width="48.462502" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.9125)">
<g transform="translate(72,-63.27)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">T</tspan>
<tspan style="font-size: 12.50px; " x="13.190665" y="0">→</tspan>
<tspan style="font-size: 12.50px; " x="30.319775" y="0">C</tspan>
</text>
</g>
</g>
</svg>, R194W, R280H and R399Q. Each of them is detailed in the text.</table>

Journal of Nucleic Acids

fig1

Figure 1

Figure 1: Influence of <i>XRCC1</i> Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair 

Journal of Nucleic Acids

Influence of XRCC1 Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair

Figure 1