Architecture of Y-Family DNA Polymerases Relevant to Translesion DNA Synthesis as Revealed in Structural and Molecular Modeling Studies

Figure 5

The little finger domain of Dpo4, showing amino acids whose R-groups contribute to the hydrophobic core (H1–H21, turquoise). Furthermore, lysine/arginine/asparagine/glutamine residues that interact with phosphate-oxygens are shown in red (L1–L9), and serine/threonine residues that interact with phosphate-oxygens are shown in pink (S1–S4). The view is toward the four anti-parallel 𝛽1–𝛽4 strands, and 𝛽1 begins to the right, while the last amino acid in 𝛽4 is shown just below it. The view is also into the face that binds duplex DNA, where the helix axis is approximately vertical. The Dpo4 coordinates are from 1SOM-B.