Expression of 𝑂⁶-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients

Figure 3

Immunohistochemical detection of MGMT in bladder tissue from patients with bladder cancer: normal urothelium (1a) and squamous metaplastic epithelium 1(b); SCC (2a) and moderately differentiated SCC (2b) sections of bilharzial bladder; invasive TCC (3a) and low grade papillary TCC (3b); non neoplastic urothelium with some dysplastic changes (4a) and grade II papillary TCC (4b); normal urothelium (5a) and invasive TCC (5b). Note that the intensity of staining is highest in the high grade section (5b). Scale bars = 100 𝜇m.