Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics

<table><i>In situ</i> chip preparation process monitored by reflectometric interference spectroscopy (RIfS). Chips were prepared in PBS at 30°C. Flow rate was 2.0 <i>μ</i>L min<sup>−1</sup>.</table>

Journal of Nucleic Acids

fig2

Figure 2

Figure 2: Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics 