Influence of a Hairpin Loop on the Thermodynamic Stability of a DNA Oligomer

Figure 4

Thermodynamics of hairpin and duplex unfolding: standard Gibbs free energy (a), standard enthalpy (b), and the corresponding entropy contribution (c) presented for each model predicted hairpin (I→S, HP→S) and duplex (D→2S) transitions as functions of temperature at [Na⁺] = 0.13M.

(a)

(b)

(c)